Journal article

Risk factors for chronic cough in adults: A systematic review and meta-analysis

J Zhang, JL Perret, AB Chang, NS Idrose, DS Bui, AJ Lowe, MJ Abramson, EH Walters, CJ Lodge, SC Dharmage

Respirology | WILEY | Published : 2022

Abstract

Despite the challenges of diagnosing and managing adult patients with chronic cough, a systematic synthesis of evidence on aetiological risk factor is lacking. We systematically searched PubMed and EMBASE to synthesize the current evidence for longitudinal associations between a wide range of risk factors and chronic cough in the general adult population, following the meta-analysis of observational studies in epidemiology (MOOSE) guidelines. The Newcastle–Ottawa scale was used to assess the quality of the included studies. Fixed-effect meta-analysis was conducted where appropriate. Of 26 eligible articles, 16 domains of risk factors were assessed. There was consistent evidence that asthma (..

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